33 California Based Alternative Health Startups

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This article showcases ImproveHerHealth.com’s top picks for the best ‘Alternative Health startups based in California’. These startups are taking a variety of approaches to innovating in the Alternative Health industry, but are all exceptional startups well worth a follow.

We selected these startups for exceptional performance in one of these categories:

  • Innovation
    • Innovative ideas
    • Innovative route to market
    • Innovative product
  • Growth
    • Exceptional growth
    • Exceptional growth strategy
  • Management
  • Societal impact

Welp Magazine (our partner website) hosts a yearly startup award honouring the most outstanding entrepreneurs and high-growth businesses in the world. If you want to enter your startup to be in the running for the top startup of 2021 or learn more about our competition click here.


1. Revel Technologies

The idea behind this startup: Revel Technologies are making the world’s first caffeine alternative.

Headquarters: Berkeley, California, United States

Industries: Alternative Medicine

Founders: Unknown

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2. Seneca Capital Group

The idea behind this startup: Seneca Capital Group creates environmental and medicinal solutions.

Headquarters: Beverly Hills, California, United States

Industries: Agriculture, Alternative Medicine, Medical, Wellness

Founders: Unknown

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3. LaughMD

The idea behind this startup: LaughMD is a TV channel and app that delivers humor as therapeutic care in hospitals, dialysis, and addiction recovery treatment facilities.

Headquarters: Burbank, California, United States

Industries: Alternative Medicine, Apps, Health Care, Hospital, Medical, TV

Founders: Frank Chindamo

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4. Regeneration

The idea behind this startup: Regeneration is a New Health Care System. Focused on Women and Children’s Health Through the Circle of Time.

Headquarters: California City, California, United States

Industries: Alternative Medicine, Artificial Intelligence, Children, Health Care, Home Health Care, Parenting, Personal Health

Founders: Cody Long, David Joseph, Dr. Golda Joseph, Dr. Michael Joseph

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5. REMD Biotherapeutics

The idea behind this startup: REMD Biotherapeutics provides medications for chronic illnesses such as metabolic diseases.

Headquarters: Camarillo, California, United States

Industries: Alternative Medicine, Biopharma, Biotechnology, Life Science, Therapeutics

Founders: Dung Thai, Francis Calzone, Hai Yan, Jingang Wang, Thomas Boone

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6. NutraMed

The idea behind this startup: Nutramed develops, manufactures, and markets tablet capsules and powder nutritional supplements in the United States and internationally.

Headquarters: Chino, California, United States

Industries: Alternative Medicine, Biotechnology, Manufacturing

Founders: Unknown

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7. NantOmics

The idea behind this startup: NantOmics develops cloud-based molecular profiling tools that help guide cancer patients.

Headquarters: Culver City, California, United States

Industries: Alternative Medicine, Biotechnology, Cloud Data Services, Genetics, Health Care, Life Science

Founders: Patrick Soon-Shiong

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8. Milagen

The idea behind this startup: Milagen is developing and commercializing innovative products to improve the quality of life of patients suffering from cancer.

Headquarters: Emeryville, California, United States

Industries: Alternative Medicine, Health Care, Health Diagnostics

Founders: Moncef Jendoubi

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9. Osh’s Affordable Pharmaceuticals

The idea behind this startup: Osh’s Affordable Pharmaceuticals produces generic drugs at low prices.

Headquarters: Fremont, California, United States

Industries: Alternative Medicine, Medical, Pharmaceutical, Retail, Sales

Founders: Alex Oshmyansky

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10. Intrinsic LifeSciences

The idea behind this startup: Intrinsic LifeSciences LLC, a life sciences company, develops in vitro diagnostic devices for clinical medicine applications

Headquarters: La Jolla, California, United States

Industries: Alternative Medicine, Biotechnology, Genetics, Health Diagnostics, Life Science

Founders: Mark Westerman, Vaughn Ostland

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11. Melt Water

The idea behind this startup: #1 Health & Drink Reminder App

Headquarters: Los Angeles, California, United States

Industries: Alternative Medicine, Health Care, Home Health Care, Medical, Mobile Apps, Sports

Founders: Dmitriy Molokov

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12. Acupuncture and Herbal Medicine

The idea behind this startup: Acupuncture and Herbal Medicine is an efficient & authentic health solution that is capable of treating a wide variety of complex symptoms.

Headquarters: Los Angeles, California, United States

Industries: Alternative Medicine, Health Care, Medical

Founders: Unknown

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13. PneumRx

The idea behind this startup: PneumRx is a medical device company focused on developing minimally-invasive solutions for unmet medical needs in pulmonary medicine.

Headquarters: Mountain View, California, United States

Industries: Alternative Medicine, Biotechnology, Health Care, Medical, Medical Device

Founders: Erin McGurk, Mark Mathis

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14. Pacific Naturopathic

The idea behind this startup: Pacific Naturopathic is a healthcare center that helps with naturopathic treatment, cancer care, and consulting.

Headquarters: Mountain View, California, United States

Industries: Alternative Medicine, Health Care, Wellness

Founders: Unknown

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15. Lighten Up Health Center

The idea behind this startup: Lighten Up Health Center provide state-of-the-art in colon hydrotherapy services and promise you the best possible experience.

Headquarters: Newport Beach, California, United States

Industries: Alternative Medicine, Health Care, Medical

Founders: Unknown

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16. Phyx

The idea behind this startup: Phyx is an on-demand chiropractic and massage therapy provided by world-class contractors.

Headquarters: Palos Verdes Estates, California, United States

Industries: Alternative Medicine, Health Care, Health Diagnostics, Personal Health, Sports, Therapeutics, Wellness

Founders: Saundia Stewart, Tim Ursich

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17. Arrinex, Inc.

The idea behind this startup: Arrinex is a privately funded medical device company based in Silicon Valley.

Headquarters: Redwood City, California, United States

Industries: Alternative Medicine, Health Care, Medical, Medical Device

Founders: Mojgan Saadat, Vahid Saadat

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18. Elica Health Centers

The idea behind this startup: Elica Health Centers is a health care center and partnership with other organizations.

Headquarters: Sacramento, California, United States

Industries: Alternative Medicine, Facilities Support Services, Fitness, Health Care, Non-Profit

Founders: Elizabeth Cassin

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19. BioCardia

The idea behind this startup: BioCardia is a clinical-stage regenerative medicine company.

Headquarters: San Carlos, California, United States

Industries: Alternative Medicine, Biotechnology, Medical, Therapeutics

Founders: Unknown

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20. Kumquat Biosciences

The idea behind this startup: Kumquat Biosciences is a biotech company developing therapies to discover oncology medicines.

Headquarters: San Diego, California, United States

Industries: Alternative Medicine, Biotechnology, Therapeutics

Founders: Pingda Ren, Yi Liu

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21. Curejoy

The idea behind this startup: Curejoy provides expert Advice on Natural Cure, Fitness & Beauty.

Headquarters: San Francisco, California, United States

Industries: Advice, Alternative Medicine, Fitness, Health Care

Founders: Dikshant Dave

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22. Chan Zuckerberg Biohub

The idea behind this startup: Chan Zuckerberg Biohub is a non-profit medical research organization started by Priscilla Chan and Mark Zuckerberg.

Headquarters: San Francisco, California, United States

Industries: Alternative Medicine, Medical, Non-Profit

Founders: Mark Zuckerberg, Priscilla Chan

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23. Aura Health

The idea behind this startup: Aura is a digital wellness ecosystem that provides personalized content & community from therapists & coaches around the world

Headquarters: San Francisco, California, United States

Industries: Alternative Medicine, Consumer, Content Discovery, Health Care, Mobile Apps, Personal Health, Wellness

Founders: Daniel Lee, Steve Lee

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24. Joint Juice

The idea behind this startup: Joint Juice, Inc. created the market’s original ready-to-drink glucosamine supplement, located in Kings Mountain, California.

Headquarters: San Francisco, California, United States

Industries: Alternative Medicine, Health Care, Professional Services

Founders: Unknown

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25. Humm.ly

The idea behind this startup: Humm.ly is making mindfulness fun and motivating through music therapy informed content!

Headquarters: San Francisco, California, United States

Industries: Alternative Medicine, Health Care, Mobile, Music, Wellness

Founders: Joanna Yu

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26. AquaRa Nutraceuticals

The idea behind this startup: Solving poorly met medical needs with nutraceuticals and natural products having strong medical rationale and robust clinical evidence.

Headquarters: San Francisco, California, United States

Industries: Alternative Medicine, Fitness, Health Care, Nutraceutical, Personal Health, Wellness

Founders: Ken Colley MD

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27. Labcyte

The idea behind this startup: Lab­cyte Inc. is the maker of Echo® Acoustic Liquid Handling systems for life sciences.

Headquarters: San Jose, California, United States

Industries: Alternative Medicine, Biotechnology, Life Science, Pharmaceutical

Founders: Richard Ellson

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28. Online Medical Card

The idea behind this startup: Get a doctor’s marijuana recommendation (medical card) in 10 minutes. It’s fast, easy, and legal.

Headquarters: Santa Ana, California, United States

Industries: Alternative Medicine, Cannabis

Founders: Unknown

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29. Apollomics

The idea behind this startup: Apollomics is a developer of oncology therapeutics that intend to harness the immune system and targeting specific molecular pathways.

Headquarters: Santa Clara, California, United States

Industries: Alternative Medicine, Biotechnology, Health Care, Pharmaceutical

Founders: Sanjeev Redkar

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30. Traditional Medicinals

The idea behind this startup: Traditional Medicinals is committed to using high-quality pharmacopoeial grade herbs and embracing ingredient purity, sustainability.

Headquarters: Sebastopol, California, United States

Industries: Alternative Medicine, Manufacturing, Sustainability

Founders: Drake Sadler, Rosemary Gladstar

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31. Stemcentrx

The idea behind this startup: Stemcentrx provides pharmaceutical services.

Headquarters: South San Francisco, California, United States

Industries: Alternative Medicine, Biotechnology, Health Diagnostics, Pharmaceutical, Therapeutics

Founders: Brian Slingerland, Scott J. Dylla

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32. Pain Management – Pain Doctor – Comprehensive Pain Management Center

The idea behind this startup: Founded by Dr. James Lin, we strive to provide an integrated approach to pain management and improve one’s daily life – pain-free.

Headquarters: Thousand Oaks, California, United States

Industries: Alternative Medicine, Health Care, Medical

Founders: Unknown

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33. Magneto-Inertial Fusion Technologies

The idea behind this startup: Solve the current crisis of worldwide shortages.

Headquarters: Tustin, California, United States

Industries: Alternative Medicine, Energy, Innovation Management

Founders: Frank Wessel

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